May 2025 BLS data · live take-home

Registered Nurses Salary in South Carolina

The median annual salary for registered nurses in South Carolina is $82,360, based on May 2025 BLS data. Here is what that salary looks like on a biweekly paycheck after taxes.

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Salary breakdown

Median wage from BLS May 2025, applied through the 2026 tax engine.

Take-home per check

2026 rates · biweekly

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Gross pay (per check)$3,168
Federal income tax-$357
Social Security-$196
Medicare-$46
State income tax (SC)-$146
Net take-home$2,423
Annual net: $62,986Effective rate: 23.5%

Median wage from BLS OEWS (May 2025, retrieved 2026-09-02). Tax estimate uses 2026 federal brackets and South Carolina state rules; local taxes excluded.

Registered Nurses pay across South Carolina scenarios

The BLS median represents the midpoint — half of registered nurses in South Carolina earn more, half earn less. Run your own number through the South Carolina paycheck calculator or compare states with the state income tax comparison.

Frequently asked questions

What is the median Registered Nurses salary in South Carolina?

The median annual salary for registered nurses in South Carolina is $82,360 (BLS OEWS, May 2025). After federal tax, FICA and South Carolina state income tax, a single filer keeps approximately $2,423 per biweekly check.

How much does a registered nurses take home in South Carolina after taxes?

On the median salary of $82,360, a single filer in South Carolina takes home approximately $2,423 every two weeks ($3,168 gross). The effective tax rate is 23.5%.

Other salaries in South Carolina

Registered Nurses salary in other states

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